Dihydroberberine is a hydrogenated, highly bioavailable derivative of the plant compound berberine. Known as "super berberine," it converts to berberine in the body. It is used at much lower doses than standard berberine, which helps minimize gastrointestinal side effects while supporting blood sugar and lipid metabolism.
Key Benefits & Mechanism
- Superior Absorption: Studies indicate that dihydroberberine provides up to 5 times the bioavailability of standard berberine, meaning smaller doses produce the same systemic effects.
- AMPK Activation: It activates AMP-activated protein kinase (AMPK), an enzyme that plays a major role in regulating glucose balance and cellular energy.
- Metabolic Support: DHB is frequently used to promote healthy blood sugar, insulin sensitivity, and weight management.
Dosage & How to Take
- Standard Doses: Typical dosages range from 100mg to 200mg daily.
- Timing: For optimal absorption and to assist with glucose spikes, it is best taken directly before or during meals.
